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Integrative literatura review: a research method to incorporate evidence in health care and nursing

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Statistical allocation methods used in randomized controlled trials on bilateral carpal tunnel syndrome: an integrative literature review

The objective of this review was to verify the available scientific evidence on allocation and concealment methods, and the statistical analyses used in randomized clinical trials (RCTs) on bilateral CTS. An integrative literature review was conducted, based on searches of databases for the period from 2014 to 2021. One-hundred-and-ten articles were found, of which 22 were considered eligible for inclusion. The statistical analyses methods used in the presence of bilateral pathologies was not clear in six (27.27%) cases and was inappropriate in another six (27.27%). A further five (22.72%) articles included only the most severely affected wrist for evaluation, while data from the right and left wrist were analyzed and described separately in four (18.18%) reports. Finally, only one (4.54%) RCT showed an adequate statistical approach. RCTs on clinical and surgical therapy of CTS do not use statistical models that include data repetition due to bilaterality when assessing outcomes.

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Chang, Y., Hsieh, S., Horng, Y., Chen, H., Lee, K., & Horng, Y. (2014). Comparative effectiveness of ultrasound and paraffin therapy in patients with carpal tunnel syndrome: a randomized trial [Comparative Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't]. BMC musculoskeletal disorders, 15, 399. http://onlinelibrary.wiley.com/o/cochrane/clcentral/articles/210/CN-01112210/frame.html

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Hopewell, S., McDonald, S., Clarke, M. J., & Egger, M. (2007). Grey literature in meta‐analyses of randomized trials of health care interventions. Cochrane Database of Systematic Reviews(2).

Huisstede, B. M., Fridén, J., Coert, J. H., Hoogvliet, P., & Group, E. H. (2014). Carpal tunnel syndrome: hand surgeons, hand therapists, and physical medicine and rehabilitation physicians agree on a multidisciplinary treatment guideline—results from the European HANDGUIDE Study. Archives of physical medicine and rehabilitation, 95(12), 2253-2263.

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Moher, D., Schulz, K. F., Altman, D. G., & Group, C. (2003). The CONSORT statement: revised recommendations for improving the quality of reports of parallel-group randomised trials. Clinical oral investigations, 7(1), 2-7.

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Shamseer, L., Hopewell, S., Altman, D. G., Moher, D., & Schulz, K. F. (2016). Update on the endorsement of CONSORT by high impact factor journals: a survey of journal “Instructions to Authors” in 2014. Trials, 17(1), 301.

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Sim, S. E., Gunasagaran, J., Goh, K. J., & Ahmad, T. S. (2018). Short-term clinical outcome of orthosis alone vs combination of orthosis, nerve, and tendon gliding exercises and ultrasound therapy for treatment of carpal tunnel syndrome. J Hand Ther. https://doi.org/10.1016/j.jht.2018.01.004

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Thoma, A., Veltri, K., Haines, T., & Duku, E. (2004). A meta-analysis of randomized controlled trials comparing endoscopic and open carpal tunnel decompression. Plastic and reconstructive surgery, 114(5), 1137-1146.

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Uribe-Quevedo, A., Ortiz, S., Rojas, D., & Kapralos, B. (2016). Hand tracking as a tool to quantify carpal tunnel syndrome preventive exercises. 2016 7th International Conference on Information, Intelligence, Systems & Applications (IISA),

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integrated literature review research methods

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Copyright (c) 2022 Sergio Murilo Georgeto; Karen Barros Parron Fernandes; Eros de Oliveira Junior; Rodrigo Antônio Carvalho Andraus

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